Small update: my silence here means I'm working on my build framework to support versions of MS-DOS 4.01 up to 6.22 and everything in between plus DR/IBM-DOS and Win95/98 DOS in later iterations, a whole slew of mouse drivers and tweaks to those, memory management by QEMM386 as well as EMM386, proper CD-ROM support, etc. I don't always have easy access to my MiSTer, so testing happens in bursts for me. The result that's beginning to surface now is a very quick method to spit out large numbers of VHD's with all sorts of subtle differences between them, so it becomes easy to make reproducible tests to find out which one works best.
By the way, I'm not using eXoDOS because that collection is more often than not "tainted" by all manner of patches and mods that weren't part of the original games. I'm only using their zipfiles in cases where I can't find originals of the games in question. I'm also going to publish many "duplicates" in different stages of patching/expansion from the original vendor. Unpatched versions of games tend to be lost to history, even though they do have relevance.
As soon as I update my website's games page again, I'll add a column to indicate the maturity of the build so you can actually see how much testing was done on each build and if a game even works on MiSter at all. This is all a work in progress between jobs and family life though, so patience is a virtue here..