Hi there.
There's definitively an issue with audio on the core. It has something missing on the implementation that emulators have.
https://github.com/MiSTer-devel/MacPlus_MiSTer/issues/7
e.g. check Lode Runner with MiniVMAC emulator and check it with our beloved core, and it's absolutely missing the Lasers and falling FX.
This core is based on Plus_Too, so I opened a ticket and gyurco asked me for documentation on how it should be implemented, but I found no information.
https://github.com/mist-devel/plus_too/issues/3
I feel there's something at low level that it is missing, maybe just a timing issue?
Could you help me on determining how FX on lode runner works and what's expecting?